Description

3-(4-Methylphenyl)-1H-1,2,4-Triazole-5-Thiol is a versatile heterocyclic organic compound featuring a triazole core substituted with a thiol group and a p-tolyl moiety. This structure makes it a valuable intermediate and building block in advanced organic synthesis, particularly for creating molecules with specific biological or material properties. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications ranging from drug discovery to polymer modification.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where the triazole-thiol pharmacophore is active.
• Agrochemical Synthesis: Used in the research and development of new fungicides, herbicides, and plant growth regulators, leveraging its heterocyclic structure for bioactivity.
• Corrosion Inhibitor Precursor: Serves as a starting material for synthesizing specialized corrosion inhibitors used in industrial cooling systems, oilfield chemicals, and metal treatment processes.
• Polymer Additive & Modifier: Acts as a monomer or cross-linking agent in the production of high-performance polymers, resins, and coatings to impart specific chemical resistance or thermal stability.
• Ligand in Coordination Chemistry: Utilized in the preparation of metal-organic frameworks (MOFs) and catalysts due to its ability to coordinate with various metal ions through its nitrogen and sulfur atoms.
• Analytical Reagent & Chelating Agent: Employed in analytical chemistry for the selective detection or complexation of specific metal ions in solution.

Basic Information

Product Name	3-(4-Methylphenyl)-1H-1,2,4-Triazole-5-Thiol
CAS No.	64310-34-5
Molecular Formula	C9H9N3S
Molecular Weight	191.25 g/mol
Synonyms	5-Mercapto-3-p-tolyl-1,2,4-triazole; 3-p-Tolyl-1H-1,2,4-triazole-5-thiol; 3-(p-Tolyl)-1H-1,2,4-triazole-5-thiol; 5-Thiol-3-(4-methylphenyl)-1,2,4-triazole; 4-Methylphenyl-1,2,4-triazole-5-thiol; 1H-1,2,4-Triazole-5-thiol, 3-(4-methylphenyl)-; 3-(4-Methylphenyl)-5-mercapto-1,2,4-triazole
EINECS	Contact for details

Quality Control

Our production of 3-(4-Methylphenyl)-1H-1,2,4-Triazole-5-Thiol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise customer specifications and consistent batch-to-batch reliability. Certificates of Analysis (COA) detailing all test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.