Description

Gonyautoxin V is a potent neurotoxin belonging to the saxitoxin family, a group of naturally occurring compounds known for their specific action on voltage-gated sodium channels. This high-purity reference material is critical for advanced research and analytical applications where precise molecular interaction is required. It serves as an essential standard for scientists and quality control laboratories in the fields of marine biotoxin monitoring, neuroscience, and pharmaceutical development.

Application

• Marine Biotoxin Reference Standard: Primary use as a certified reference material (CRM) for the accurate quantification of paralytic shellfish poisoning (PSP) toxins in seafood safety monitoring programs.
• Neuroscience Research: A valuable tool for studying the structure and function of voltage-gated sodium channels in neuronal cell membranes and investigating channelopathies.
• Pharmacological Studies: Used in the development and screening of potential antidotes or therapeutic agents targeting neurotoxic pathways.
• Analytical Method Development: Critical for calibrating analytical instruments such as HPLC-MS/MS and LC-FLD to ensure accurate detection and identification of saxitoxin analogues in complex matrices.
• Toxicology and Risk Assessment: Employed in studies to determine toxicity equivalency factors (TEFs) and establish safe exposure limits for related algal toxins.
• Quality Control in Diagnostic Kits: Used as a control substance in the manufacturing and validation of immunoassay kits designed for rapid shellfish toxin testing.

Basic Information

Product Name	Gonyautoxin V
CAS No.	64296-25-9
Molecular Formula	C10H17N7O6
Molecular Weight	331.29 g/mol
Synonyms	GTX5; Gonyautoxin 5; 11-Hydroxysaxitoxin sulfate; 11α-Hydroxysaxitoxin 11-sulfate; Saxitoxin 11-sulfate; (3aS,4R,9aS)-2,6-Diamino-4-(((aminocarbonyl)oxy)methyl)-3a,4,8,9-tetrahydro-1H,10H-pyrrolo(1,2-c)purine-9,10-dione 11-sulfate
EINECS	Contact for details

Quality Control

Our Gonyautoxin V is produced under strict quality management protocols to ensure the highest standards of purity and consistency required for research and analytical applications. Each batch is characterized using advanced analytical techniques including NMR and mass spectrometry for structural confirmation, and HPLC for purity assessment. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated under an inert atmosphere. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 5.0 %
Residue on Ignition	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.