Description

4,4,5,5,5-Pentafluoro-1-(4-Fluoro-Phenyl)-Pentane-1,3-Dione is a specialized fluorinated diketone compound, serving as a high-value building block in advanced organic synthesis. Its unique structure, featuring a pentafluoroalkyl chain and a fluorinated aromatic ring, makes it a critical intermediate for introducing specific fluorine motifs into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require precise fluorination to modulate the biological activity, metabolic stability, and physicochemical properties of their products.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated scaffolds to enhance bioavailability and metabolic resistance.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where fluorine atoms improve efficacy and environmental persistence.
• Ligand Precursor in Catalysis: Serves as a precursor for β-diketonate ligands used in coordination chemistry and metal-organic frameworks (MOFs), especially those involving lanthanides or other metals.
• Material Science Research: Employed in the creation of fluorinated polymers and advanced organic electronic materials to fine-tune electronic properties and stability.
• Chemical Synthesis Reagent: Acts as a versatile reagent in organic synthesis for condensation reactions, cyclization processes, and the introduction of fluorinated acetyl groups.

Basic Information

Product Name	4,4,5,5,5-Pentafluoro-1-(4-Fluoro-Phenyl)-Pentane-1,3-Dione
CAS No.	64287-12-3
Molecular Formula	C11H6F6O2
Molecular Weight	284.15 g/mol
Synonyms	1-(4-Fluorophenyl)-4,4,5,5,5-pentafluoropentane-1,3-dione; 4,4,5,5,5-Pentafluoro-1-(p-fluorophenyl)-1,3-pentanedione; 1,3-Pentanedione, 4,4,5,5,5-pentafluoro-1-(4-fluorophenyl)-; Pentafluoro-1-(4-fluorophenyl)pentane-1,3-dione; 4-Fluorophenyl pentafluoropropionylmethane; HFA-FDK (common abbreviation in fluorochemical contexts); 4,4,5,5,5-Pentafluoro-1-(4-fluoro-phenyl)-pentan-1,3-dion
EINECS	Contact for details

Quality Control

Our 4,4,5,5,5-Pentafluoro-1-(4-Fluoro-Phenyl)-Pentane-1,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Handle and store in accordance with good laboratory/industrial practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.