Description

(2S)-2,3-Dihydro-8-Hydroxy-3α-(5-Hydroxy-2,4-Dimethoxyphenyl)-2β-(Hydroxymethyl)-5-Methoxy-7H-1,4-Dioxino[2,3-C]Xanthen-7-One is a complex, high-purity xanthone derivative of significant interest in advanced chemical synthesis and research. This compound matters for its role as a key chiral intermediate or reference standard in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and specialty chemical manufacturers engaged in cutting-edge organic synthesis and process development.

Application

This specialized xanthone derivative serves critical functions in high-value research and manufacturing sectors:

• Pharmaceutical Intermediate: Acts as a key chiral building block in the synthesis of complex drug candidates, particularly in oncology and antiviral research.
• Analytical Reference Standard: Used for method development, validation, and quality control in HPLC and LC-MS analysis within pharmaceutical and academic laboratories.
• Biochemical Research: Employed in studies exploring enzyme inhibition, receptor binding, and other biological activity assays due to its specific structural motifs.
• Fine Chemical Synthesis: Serves as a precursor for synthesizing more complex natural product analogs and novel chemical entities in process chemistry.
• Academic & Institutional Research: Utilized in universities and research institutes for investigating reaction mechanisms, asymmetric synthesis, and the properties of oxygenated heterocycles.

Basic Information

Product Name	(2S)-2,3-Dihydro-8-Hydroxy-3α-(5-Hydroxy-2,4-Dimethoxyphenyl)-2β-(Hydroxymethyl)-5-Methoxy-7H-1,4-Dioxino[2,3-C]Xanthen-7-One
CAS No.	64280-47-3
Molecular Formula	C25H22O10
Molecular Weight	482.44 g/mol
Synonyms	8-Hydroxy-3α-(5-hydroxy-2,4-dimethoxyphenyl)-2β-(hydroxymethyl)-5-methoxy-2,3-dihydro-7H-1,4-dioxino[2,3-c]xanthen-7-one; (2S)-form; CAS 64280-47-3; 1,4-Dioxino[2,3-c]xanthen-7-one derivative; Polyoxygenated xanthone derivative; Chiral xanthone intermediate.
EINECS	Contact for details

Quality Control

Our (2S)-2,3-Dihydro-8-Hydroxy-3α-(5-Hydroxy-2,4-Dimethoxyphenyl)-2β-(Hydroxymethyl)-5-Methoxy-7H-1,4-Dioxino[2,3-C]Xanthen-7-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive spectroscopic identification (NMR, MS) to ensure structural integrity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.