Description

3-Fluoro-2,2-Dimethyl-Propionic Acid is a fluorinated carboxylic acid derivative characterized by its gem-dimethyl and fluorine substituents, which impart unique steric and electronic properties. This compound serves as a valuable building block in advanced organic synthesis, enabling the introduction of a sterically hindered, fluorine-containing moiety. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting metabolic diseases and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science: Employed in the synthesis of fluorinated polymers and specialty chemicals that require specific surface properties, such as low surface energy or chemical resistance.
• Fluorine Chemistry Research: A fundamental reagent in academic and industrial laboratories studying the effects of fluorine substitution on molecular reactivity and physicochemical properties.

Basic Information

Product Name	3-Fluoro-2,2-Dimethyl-Propionic Acid
CAS No.	64241-77-6
Molecular Formula	C5H9FO2
Molecular Weight	120.12 g/mol
Synonyms	3-Fluoro-2,2-dimethylpropanoic acid; 2,2-Dimethyl-3-fluoropropionic acid; 3-Fluoro-2,2-dimethylpropionic acid; 3-Fluoro-2,2-dimethylpropanoic acid; 64241-77-6; α,α-Dimethyl-β-fluoropropionic acid; β-Fluoro-alpha,α-dimethylpropionic acid; Propanoic acid, 3-fluoro-2,2-dimethyl-
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2,2-Dimethyl-Propionic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) upon request, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and a strong acid/organic solvent. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.