Description

[(1R,2S,3R,5R)-2,6,6-Trimethylbicyclo[3.1.1]hept-3-yl]borane is a highly versatile and stereochemically defined organoborane reagent, essential for precise asymmetric synthesis. Its value lies in its ability to act as a chiral building block, enabling the introduction of the pinane skeleton into complex molecular architectures with high enantioselectivity. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing chiral intermediates, natural product analogs, and novel active ingredients.

Application

• Asymmetric Synthesis: Key chiral reagent for hydroboration reactions to produce enantiomerically enriched alcohols.
• Pharmaceutical Intermediates: Construction of chiral scaffolds for active pharmaceutical ingredients (APIs), particularly in antiviral and cardiovascular drug research.
• Agrochemical Development: Synthesis of chiral ligands and bioactive molecules for novel pesticides and herbicides.
• Fine Chemical Manufacturing: Production of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Material Science Research: Precursor for boron-containing polymers or advanced organic electronic materials.
• Catalyst Ligand Synthesis: Building block for creating novel chiral ligands used in transition metal catalysis.

Basic Information

Product Name	[(1R,2S,3R,5R)-2,6,6-Trimethylbicyclo[3.1.1]hept-3-yl]borane
CAS No.	64234-27-1
Molecular Formula	C10H19B
Molecular Weight	150.07 g/mol
Synonyms	(1R,2S,3R,5R)-(-)-Isopinocampheylborane; (-)-IpcBH2; (1R,2S,3R,5R)-3-Boranylbicyclo[3.1.1]heptane, 2,6,6-trimethyl-; (-)-Isopinocampheylborane; IpcBH2; Chiral isopinocampheylborane; (1R)-(-)-Isopinocampheylborane; α-Pinene-derived borane
EINECS	Contact for details

Quality Control

Our [(1R,2S,3R,5R)-2,6,6-Trimethylbicyclo[3.1.1]hept-3-yl]borane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data (GC, HPLC) and spectroscopic confirmation (NMR) are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. Due to its moisture-sensitive and easily oxidized nature, the container must be kept sealed and allowed to reach room temperature before opening to prevent condensation and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution or solid
Identification (NMR)	Conforms to structure
Assay (by Titration)	≥ 95.0%
Chiral Purity (Enantiomeric Excess)	≥ 98.0% ee
Solvent (if supplied as solution)	Specified (e.g., Tetrahydrofuran)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.