Description

3-Amino-1,1,1-Trifluoro-2-(Trifluoromethyl)Propan-2-Ol is a high-value, fluorinated amino alcohol building block, distinguished by its unique structure containing both amino and multiple trifluoromethyl groups. This compound is critical for introducing fluorine atoms into target molecules, thereby enhancing their metabolic stability, lipophilicity, and bioavailability. It is primarily sought after by R&D and process chemists in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms contribute to improved efficacy and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and specialty materials with unique surface properties and chemical resistance.
• Fluorine Chemistry Building Block: Essential for introducing the -CF3 moiety into complex organic molecules in medicinal and synthetic chemistry.

Basic Information

Product Name	3-Amino-1,1,1-Trifluoro-2-(Trifluoromethyl)Propan-2-Ol
CAS No.	64139-78-2
Molecular Formula	C5H5F6NO
Molecular Weight	209.09 g/mol
Synonyms	3-Amino-1,1,1-trifluoro-2-(trifluoromethyl)propan-2-ol; 2-(Trifluoromethyl)-3-amino-1,1,1-trifluoropropan-2-ol; 3-Amino-1,1,1,2-tetrafluoro-2-(trifluoromethyl)propan-2-ol (tautomer); 3-Aminohexafluoroisobutanol; Hexafluoro-2-methyl-3-aminopropan-2-ol; Aminohexafluoroisobutyl alcohol
EINECS	Contact for details

Quality Control

Our 3-Amino-1,1,1-Trifluoro-2-(Trifluoromethyl)Propan-2-Ol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.