Description

2,3,3A,8A-Tetrahydro-3A-Hydroxy-1,1-Dimethylcyclopent[A]Inden-8(1H)-One is a specialized organic compound with a complex fused-ring structure, serving as a key synthetic intermediate in advanced organic chemistry. Its unique molecular framework makes it a valuable building block for the synthesis of complex molecules, particularly in the pharmaceutical and fine chemical sectors. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs), agrochemicals, and high-performance materials who require reliable access to high-purity, structurally defined intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly those with complex polycyclic structures.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its functionalized cyclopentane-indane core.
• Fine Chemical Production: Serves as a versatile building block for creating specialty chemicals, including fragrances, dyes, and performance additives.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic synthesis, asymmetric catalysis, and total synthesis projects.
• Material Science Precursor: Potential use in the development of organic electronic materials or liquid crystals due to its rigid, fused-ring system.

Basic Information

Product Name	2,3,3A,8A-Tetrahydro-3A-Hydroxy-1,1-Dimethylcyclopent[A]Inden-8(1H)-One
CAS No.	64129-27-7
Molecular Formula	C₁₄H₂₀O₂
Molecular Weight	220.31 g/mol
Synonyms	3a-Hydroxy-1,1-dimethyl-2,3,3a,8a-tetrahydro-1H-cyclopenta[a]inden-8(5H)-one; 1,1-Dimethyl-3a-hydroxy-2,3,3a,8a-tetrahydro-1H-cyclopenta[a]inden-8(5H)-one; 3a-Hydroxy-1,1-dimethyl-2,3,3a,8a-tetrahydrocyclopenta[a]inden-8-one; Tetrahydro dimethylhydroxy cyclopentaindenone; 64129-27-7; Light-sensitive ketone intermediate; Fused-ring hydroxy ketone building block
EINECS	Contact for details

Quality Control

Our 2,3,3A,8A-Tetrahydro-3A-Hydroxy-1,1-Dimethylcyclopent[A]Inden-8(1H)-One is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere if prolonged exposure is anticipated to prevent potential degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.