Description

(3Ar,4R)-7β-[(R)-1,5-Dimethyl-4-Hexenyl]-3Aα,5,6,7,8,8Aβ-Hexahydro-1-Methylspiro[Azulene-4(3H),2'-Oxiran]-8β-Ol is a high-purity, complex organic compound featuring a unique spirocyclic and azulene-based structure. This compound serves as a critical chiral intermediate in advanced organic synthesis, enabling the production of high-value, stereochemically defined molecules. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for developing novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex stereochemistry.
• Asymmetric Synthesis: Utilized in catalytic and stoichiometric asymmetric reactions to construct molecules with high enantiomeric purity.
• Natural Product Analog Synthesis: Serves as a core scaffold for the research and synthesis of analogs of complex natural products with potential biological activity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Advanced Material Precursor: Potential use in the development of specialty chemicals and advanced organic materials with specific optical or electronic properties.
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in research and manufacturing.

Basic Information

Product Name	(3Ar,4R)-7β-[(R)-1,5-Dimethyl-4-Hexenyl]-3Aα,5,6,7,8,8Aβ-Hexahydro-1-Methylspiro[Azulene-4(3H),2'-Oxiran]-8β-Ol
CAS No.	64118-74-7
Molecular Formula	C₂₂H₃₄O₂
Molecular Weight	330.51 g/mol
Synonyms	7β-[(R)-1,5-Dimethyl-4-hexenyl]-3aα,5,6,7,8,8aβ-hexahydro-1-methylspiro[azulene-4(3H),2'-oxiran]-8β-ol; Spiro[azulene-4(3H),2'-oxiran]-8β-ol derivative; Azulene epoxide derivative; Chiral azulene-spirooxirane intermediate; (3aR,4R,7R,8aR)-7-[(1R)-1,5-Dimethylhex-4-en-1-yl]-1-methyl-3a,4,5,6,7,8,8a,8b-octahydrospiro[azulene-4,2'-oxiran]-8-ol
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical and enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be sensitive to prolonged exposure to air and moisture; containers should be kept sealed under an inert atmosphere when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.