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Lithium B-Isopinocampheyl-9-Borabicyclo[3.3.1]Nonyl Hydride CAS NO 64081-12-5
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CAS No.:64081-12-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Lithium B-Isopinocampheyl-9-Borabicyclo[3.3.1]Nonyl Hydride is a highly specialized, chiral organoborane reagent. This compound matters as a powerful and selective reducing agent, particularly valued for its ability to deliver hydride with high stereochemical control. It is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries who require precise asymmetric synthesis, such as in the production of chiral active pharmaceutical ingredients (APIs) and advanced intermediates.
Application
- Asymmetric Reduction of Prochiral Ketones: Enantioselective synthesis of secondary alcohols for pharmaceutical building blocks.
- Chiral Auxiliary in Organic Synthesis: Used to introduce stereocenters in complex molecule construction.
- Pharmaceutical Intermediate Production: Key reagent in the synthesis of optically pure drug candidates and APIs.
- Fine Chemical and Specialty Chemical Manufacturing: For producing high-value chiral compounds used in agrochemicals and materials science.
- Academic and R&D Laboratories: A critical tool for methodological development in synthetic organic chemistry.
- Catalyst and Ligand Precursor: Can be utilized in the preparation of other chiral boron-based catalysts.
Basic Information
| Product Name | Lithium B-Isopinocampheyl-9-Borabicyclo[3.3.1]Nonyl Hydride |
| CAS No. | 64081-12-5 |
| Molecular Formula | C19H34BLi |
| Molecular Weight | 280.23 g/mol |
| Synonyms | Lithium B-Isopinocampheyl-9-BBN Hydride; Lithium Isopinocampheyl-9-Borabicyclo[3.3.1]nonane Hydride; Lithium (1R,2S,5R)-(-)-Isopinocampheyl-9-borabicyclo[3.3.1]nonyl Hydride; (-)-B-Isopinocampheyl-9-borabicyclo[3.3.1]nonane, Lithium Salt; Lithium (Ipc)2BH; Lithium Diisopinocampheylborohydride (related class); Alpine-Borane® Reagent (related commercial name); Chiral Borohydride Reagent |
| EINECS | Contact for details |
Quality Control
Our Lithium B-Isopinocampheyl-9-Borabicyclo[3.3.1]Nonyl Hydride is manufactured under stringent conditions to ensure batch-to-batch consistency and high chiral purity. Quality is verified through advanced analytical techniques including NMR, HPLC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and assay is provided with each shipment to support your quality assurance protocols.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, and well-ventilated place. This material is hygroscopic (moisture-sensitive) and easily oxidized (store under inert atmosphere). Keep away from strong acids and oxidizing agents.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or suspension |
| Identification (NMR) | Conforms to structure |
| Assay (Titration) | ≥ 95.0% |
| Enantiomeric Excess (Chiral HPLC) | ≥ 98.0% ee |
| Moisture Content (KF) | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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