Description

4-Hydroxyphenylmalonic Acid is a versatile aromatic dicarboxylic acid derivative that serves as a key synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both phenolic and malonic acid functionalities, makes it a valuable building block for constructing complex molecules with tailored properties. This compound is particularly relevant for research and development in the pharmaceutical and fine chemical sectors, where it is utilized in the synthesis of active pharmaceutical ingredients (APIs) and specialty polymers.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly those requiring a phenolic or dicarboxylate scaffold.
• Fine Chemical Synthesis: Serves as a specialized building block for creating advanced organic compounds, including ligands, catalysts, and complex organic frameworks in research laboratories.
• Polymer Chemistry: Used in the development of novel polymeric materials, where its dual carboxylic acid groups can participate in condensation reactions to form polyesters or polyamides with specific properties.
• Biochemical Research: Acts as a substrate or inhibitor analog in enzymatic studies, particularly those involving enzymes that interact with phenolic or dicarboxylic acid compounds.
• Agrochemical Development: Employed in the research and synthesis of new crop protection agents and plant growth regulators.
• Material Science: Investigated for use in the creation of organic electronic materials, metal-organic frameworks (MOFs), and other functional materials.

Basic Information

Product Name	4-Hydroxyphenylmalonic Acid
CAS No.	64076-52-4
Molecular Formula	C9H8O5
Molecular Weight	196.16 g/mol
Synonyms	2-(4-Hydroxyphenyl)malonic Acid; (4-Hydroxyphenyl)propanedioic Acid; 4-Hydroxybenzylmalonic Acid; p-Hydroxyphenylmalonic Acid; 1-Carboxy-2-(4-hydroxyphenyl)ethanoic Acid; α-Carboxy-4-hydroxyhydrocinnamic Acid; 4-HPMA
EINECS	Contact for details

Quality Control

Our 4-Hydroxyphenylmalonic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) that include results from HPLC, NMR, and other relevant spectroscopic and chromatographic methods. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed after opening to minimize exposure to atmospheric moisture and light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.