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4-Amino-n-[1-[(2R)-5α-[[4,6-Dideoxy-4-(Methylamino)-α-D-Glucopyranosyl]Oxy]Tetrahydro-6β-Methyl-2H-Pyran-2β-Yl]-1,2-Dihydro-2-Oxopyrimidin-4-Yl]Benzamide CAS NO 64040-47-7
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CAS No.:64040-47-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
4-Amino-n-[1-[(2R)-5α-[[4,6-Dideoxy-4-(Methylamino)-α-D-Glucopyranosyl]Oxy]Tetrahydro-6β-Methyl-2H-Pyran-2β-Yl]-1,2-Dihydro-2-Oxopyrimidin-4-Yl]Benzamide is a complex, high-purity chemical intermediate of significant interest in advanced pharmaceutical synthesis. This compound is valued for its specific structural features, which make it a critical building block in the development of novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the synthesis of specialized active pharmaceutical ingredients (APIs) and reference standards.
Application
- Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of novel antibiotic and antimicrobial agents.
- Active Pharmaceutical Ingredient (API) Synthesis: Used in the complex multi-step synthesis of target drug molecules, particularly in the aminoglycoside and nucleoside analog classes.
- Biochemical Research: Employed as a standard or reagent in studies investigating molecular mechanisms of action and structure-activity relationships (SAR).
- Reference Standard: Supplied as a high-purity compound for analytical method development, validation, and quality control in regulatory submissions.
- Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot and commercial manufacturing scales.
Basic Information
| Product Name | 4-Amino-n-[1-[(2R)-5α-[[4,6-Dideoxy-4-(Methylamino)-α-D-Glucopyranosyl]Oxy]Tetrahydro-6β-Methyl-2H-Pyran-2β-Yl]-1,2-Dihydro-2-Oxopyrimidin-4-Yl]Benzamide |
| CAS No. | 64040-47-7 |
| Molecular Formula | C24H31N5O7 |
| Molecular Weight | 501.53 g/mol |
| Synonyms | 4-Amino-N-[1-[(2R,5S,6R)-5-[[4,6-Dideoxy-4-(methylamino)-α-D-glucopyranosyl]oxy]-6-methyltetrahydro-2H-pyran-2-yl]-2-oxo-1,2-dihydropyrimidin-4-yl]benzamide; 4'-Amino-4-demethylamino-4,6-dideoxy-α-D-glucopyranosyl paromamine derivative; Paromamine related compound; Antibiotic intermediate 64040-47-7; 4-Aminobenzamide nucleoside analog; 4-Demethylamino-4,6-dideoxyglucose paromamine benzamide |
| EINECS | Contact for details |
Quality Control
Our production of 4-Amino-n-[1-[(2R)-5α-[[4,6-Dideoxy-4-(Methylamino)-α-D-Glucopyranosyl]Oxy]Tetrahydro-6β-Methyl-2H-Pyran-2β-Yl]-1,2-Dihydro-2-Oxopyrimidin-4-Yl]Benzamide adheres to stringent quality protocols suitable for pharmaceutical R&D and manufacturing. Each batch undergoes comprehensive analytical testing, including HPLC purity analysis, residual solvent screening, and structural confirmation to ensure identity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 2.0% |
| Residual Solvents (GC) | Complies with ICH Q3C guidelines |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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