Description

1,2,3-Propanetricarboxylic Acid Tris(Fluoromethyl) Ester is a specialized fluorinated derivative of citric acid, offering unique reactivity and stability profiles due to the introduction of fluoromethyl groups. This compound is valued for its role as a versatile building block in advanced organic synthesis, particularly where the introduction of fluorine atoms is desired to modify physical, chemical, or biological properties. It serves critical needs in the research and development of pharmaceuticals, agrochemicals, and high-performance materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of fluorinated active pharmaceutical ingredients (APIs) to enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Serves as a key precursor for developing novel fluorinated pesticides and herbicides with improved efficacy and environmental profiles.
• Advanced Material Precursor: Employed in the production of fluorinated polymers, coatings, and liquid crystals that require specific thermal, chemical, or surface properties.
• Organic Synthesis Building Block: Acts as a trifunctional reagent for introducing fluoromethyl ester groups in complex molecule construction, useful in medicinal chemistry and material science.
• Ligand and Catalyst Development: Utilized in the design of fluorinated ligands for metal-organic frameworks (MOFs) or asymmetric catalysis.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research exploring new reactions and properties of organofluorine compounds.

Basic Information

Product Name	1,2,3-Propanetricarboxylic Acid Tris(Fluoromethyl) Ester
CAS No.	63991-73-1
Molecular Formula	C9H9F3O6
Molecular Weight	270.16 g/mol
Synonyms	Tris(fluoromethyl) 1,2,3-propanetricarboxylate; Tris(fluoromethyl) citrate; Citric Acid Tris(fluoromethyl) Ester; Fluoromethyl Citrate; 1,2,3-Tricarboxypropane Tris(fluoromethyl) Ester; Propanetricarboxylic Acid Tris(fluoromethyl) Ester; 2-Hydroxy-1,2,3-propanetricarboxylic Acid Tris(fluoromethyl) Ester
EINECS	Contact for details

Quality Control

Our 1,2,3-Propanetricarboxylic Acid Tris(Fluoromethyl) Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets precise customer specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.