Description

3,5-Difluorosalicylaldehyde (97%) is a fluorinated derivative of salicylaldehyde, serving as a versatile and high-value organic building block. Its molecular structure, featuring two fluorine atoms at the meta positions of the phenolic ring, makes it a critical intermediate for synthesizing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop novel active ingredients and functional ligands.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Used to create advanced fluorinated pesticides and herbicides, leveraging fluorine's ability to enhance bioavailability and metabolic stability.
• Ligand and Catalyst Development: Acts as a chelating agent for constructing metal-organic frameworks (MOFs) and catalysts used in asymmetric synthesis.
• Fluorescent Probe and Dye Manufacturing: Serves as a starting material for developing sensitive fluorophores and molecular sensors.
• Organic Electronic Materials: A building block for synthesizing novel organic semiconductors and charge-transport materials.
• Academic and R&D: Employed in medicinal chemistry and material science research for structure-activity relationship (SAR) studies.

Basic Information

Product Name	3,5-Difluorosalicylaldehyde (97%)
CAS No.	63954-77-8
Molecular Formula	C7H4F2O2
Molecular Weight	158.10 g/mol
Synonyms	2-Hydroxy-3,5-difluorobenzaldehyde; 3,5-Difluoro-2-hydroxybenzaldehyde; Salicylaldehyde, 3,5-difluoro-; 3,5-Difluoro-2-formylphenol; 3,5-Difluorosalicylaldehyde; 2-Formyl-4,6-difluorophenol
EINECS	Contact for details

Quality Control

Our 3,5-Difluorosalicylaldehyde is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure identity, purity, and consistency meet the specified 97% minimum assay. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.