Description

4-Fluoro-2-Hydroxybutyric Acid Methyl Ester is a valuable fluorinated chiral building block and synthetic intermediate. This compound matters for its role in introducing fluorine atoms and hydroxy ester functionalities into complex molecular architectures, enabling the fine-tuning of physicochemical and biological properties. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of fluorinated active pharmaceutical ingredients (APIs), including potential protease inhibitors and other bioactive molecules.
• Agrochemical Synthesis: Building block for creating novel fluorinated pesticides and herbicides, where the fluorine atom can enhance stability, bioavailability, and activity.
• Organic Synthesis & Catalysis: Versatile precursor in asymmetric synthesis and cross-coupling reactions for constructing complex, fluorinated organic compounds.
• Material Science Research: Used in the development of specialty polymers and liquid crystals where fluorinated segments impart unique chemical resistance and surface properties.
• Biochemical Research: Serves as a probe or substrate in enzymatic studies, particularly for investigating the metabolism and effects of fluorinated compounds.

Basic Information

Product Name	4-Fluoro-2-Hydroxybutyric Acid Methyl Ester
CAS No.	63904-99-4
Molecular Formula	C5H9FO3
Molecular Weight	136.12 g/mol
Synonyms	Methyl 4-Fluoro-2-Hydroxybutanoate; Methyl 4-Fluoro-2-Hydroxybutyrate; 2-Hydroxy-4-fluorobutanoic Acid Methyl Ester; (R/S)-Methyl 4-Fluoro-2-Hydroxybutyrate; 4-Fluoro-2-Hydroxybutanoic Acid Methyl Ester; FAHBME; 4-Fluoro-2-hydroxy-butyric acid methyl ester
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Hydroxybutyric Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Optical Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.