Description

Methyl 2,3,3,4,4,4-Hexafluoro-2-Bromobutyrate is a specialized fluorinated organic building block, valued for its unique combination of a reactive bromine atom and a hexafluorobutyl ester group. This compound is critical for introducing fluorinated segments into target molecules, significantly altering their physical, chemical, and biological properties. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, where fluorine atoms can enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging fluorine's ability to increase lipophilicity and environmental persistence of active ingredients.
• Fluorinated Polymer & Material Science: Serves as a monomer or modifier for creating specialty polymers with enhanced chemical resistance, thermal stability, and unique surface properties.
• Liquid Crystal & Electronic Materials: Employed in the synthesis of fluorinated components for liquid crystal displays (LCDs) and dielectric materials due to its impact on polarizability and intermolecular forces.
• Organic Synthesis & Catalysis: Acts as a versatile reagent in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic substitutions to construct complex fluorinated architectures.
• Research & Development: A valuable tool in academic and industrial R&D for exploring structure-activity relationships (SAR) and developing new fluorination methodologies.

Basic Information

Product Name	Methyl 2,3,3,4,4,4-Hexafluoro-2-Bromobutyrate
CAS No.	63867-09-4
Molecular Formula	C5H3BrF6O2
Molecular Weight	264.97 g/mol
Synonyms	2-Bromo-2,3,3,4,4,4-hexafluorobutanoic acid methyl ester; Methyl 2-bromo-2,3,3,4,4,4-hexafluorobutanoate; 2,3,3,4,4,4-Hexafluoro-2-bromobutyric acid methyl ester; Hexafluorobromobutyric Acid Methyl Ester; Methyl α-Bromo-β,β,γ,γ,γ-pentafluorobutyrate; MFHBB; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Every batch of Methyl 2,3,3,4,4,4-Hexafluoro-2-Bromobutyrate is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic processes. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with exacting industry standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area, away from heat sources and incompatible materials such as strong bases. Due to its highly volatile nature, ensure containers are securely sealed. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.8 g/mL
Refractive Index (n20D)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.