Description

(4ξ)-13,20-Epoxy-2,11β,12α-Trihydroxy-15β-[(3-Methyl-1-Oxo-2-Butenyl)Oxy]-3,16-Dioxopicras-1-En-21-Oic Acid Methyl Ester is a complex, highly functionalized triterpenoid derivative, specifically a methyl ester of a modified quassinoid skeleton. This compound matters as a sophisticated chemical intermediate and a key scaffold for advanced research in medicinal chemistry and pharmacology, offering a unique structural platform for the development of novel bioactive molecules. It is primarily needed by research institutions and pharmaceutical R&D departments focused on semi-synthetic drug discovery, natural product chemistry, and the investigation of cytotoxic or antiparasitic agents.

Application

• Pharmaceutical Research Intermediate: Serves as a critical building block for the semi-synthesis of novel quassinoid analogs with potential therapeutic activities.
• Medicinal Chemistry Probe: Used as a scaffold to study structure-activity relationships (SAR) in the development of anticancer or antimalarial agents.
• Natural Product Synthesis: Acts as a key intermediate in the total or partial synthesis of complex natural products for biological evaluation.
• Biochemical Research: Employed in studies investigating enzyme inhibition, particularly targeting pathways relevant to cell proliferation or parasite survival.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for the identification and quantification of related compounds.
• Academic Research: Utilized in university and institutional labs for advanced organic chemistry research and methodology development.

Basic Information

Item	Details
Product Name	(4ξ)-13,20-Epoxy-2,11β,12α-Trihydroxy-15β-[(3-Methyl-1-Oxo-2-Butenyl)Oxy]-3,16-Dioxopicras-1-En-21-Oic Acid Methyl Ester
CAS No.	63744-82-1
Molecular Formula	C31H38O11
Molecular Weight	586.63 g/mol
Synonyms	Methyl (4ξ)-13,20-epoxy-2,11β,12α-trihydroxy-15β-[(3-methyl-1-oxo-2-butenyl)oxy]-3,16-dioxopicras-1-en-21-oate; Bruceine D Methyl Ester; 13,20-Epoxy-2,11,12-trihydroxy-15-[(3-methyl-1-oxo-2-butenyl)oxy]-3,16-dioxopicras-1-en-21-oic acid methyl ester; A derivative of Bruceine D; Quassinoid methyl ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to a cGMP-compliant quality management system for traceability and consistency, ensuring reliable performance for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or Certificate of Analysis. This compound is likely light-sensitive and may be hygroscopic; store in a cool, dry place under an inert atmosphere if long-term stability is required. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.