Description

2(3H)-Naphthalenone, 1-Fluoro-4,4a,5,6,7,8-hexahydro- is a fluorinated, partially saturated naphthalenone derivative, a valuable synthetic intermediate in advanced organic chemistry. Its unique structure, featuring a fluorine atom on a reduced naphthalene core, makes it a critical building block for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors, where it is used to introduce fluorinated motifs that can enhance bioavailability, metabolic stability, and biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) agents and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom can improve lipophilicity and target binding.
• Material Science Research: Acts as a monomer or building block for creating specialized fluorinated polymers and organic electronic materials.
• Organic Synthesis Scaffold: Employed in medicinal chemistry for library synthesis and structure-activity relationship (SAR) studies due to its versatile functionalization points.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research focused on the reactivity and effects of fluorine in complex organic systems.

Basic Information

Product Name	2(3H)-Naphthalenone, 1-Fluoro-4,4a,5,6,7,8-hexahydro-
CAS No.	63742-04-1
Molecular Formula	C₁₀H₁₁FO
Molecular Weight	166.19 g/mol
Synonyms	1-Fluoro-4,4a,5,6,7,8-hexahydro-2(3H)-naphthalenone; 1-Fluoro-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one; 1-Fluoro-4,4a,5,6,7,8-hexahydro-2-naphthalenone; 1-Fluoro-4,4a,5,6,7,8-hexahydro-2H-naphthalen-2-one; 1-Fluoro-4,4a,5,6,7,8-hexahydronaphthalen-2-one; 1-Fluoro-4,4a,5,6,7,8-hexahydro-2(3H)-naphthalenone; Fluorinated hexahydronaphthalenone; 1-Fluorohexahydronaphthalenone
EINECS	Contact for details

Quality Control

Our 2(3H)-Naphthalenone, 1-Fluoro-4,4a,5,6,7,8-hexahydro- is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.