Description

4-[(4-Fluorophenoxy)Methyl]Piperidine CAS NO 63608-35-5 is a versatile fluorinated piperidine derivative, a high-value intermediate prized for its role in constructing complex molecular architectures. Its core value lies in enabling the synthesis of advanced pharmaceutical compounds and agrochemicals, where the introduction of fluorine and the piperidine moiety is critical for modulating biological activity and physicochemical properties. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorophenoxy group enhances efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of novel polymers and liquid crystals with tailored properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and receptor interactions in biological systems.

Basic Information

Product Name	4-[(4-Fluorophenoxy)Methyl]Piperidine
CAS No.	63608-35-5
Molecular Formula	C12H16FNO
Molecular Weight	209.26 g/mol
Synonyms	4-[(4-Fluorophenoxy)methyl]piperidine; 1-(4-Fluorophenoxymethyl)piperidine; 4-(4-Fluorophenoxymethyl)piperidine; Piperidine, 4-[(4-fluorophenoxy)methyl]-; 4-(4-Fluorobenzyloxy)piperidine; 4-Fluorophenoxymethylpiperidine; 4-Piperidinylmethyl 4-fluorophenyl ether
EINECS	Contact for details

Quality Control

Our 4-[(4-Fluorophenoxy)Methyl]Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.