Description

2-Bromo-3'-Chloro-4'-Fluoroacetophenone, 96% is a high-purity, multi-halogenated acetophenone derivative serving as a critical building block in advanced organic synthesis. Its precise halogen substitution pattern makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring halogenated aromatic ketone motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the halogen atoms contribute to biological activity and stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to synthesize complex ligands for catalytic systems.
• Chemical Biology Probes: Useful for creating tagged molecules or probes for studying biological mechanisms due to its reactive ketone and halogen groups.
• Custom Synthesis and R&D: A versatile starting material for contract research organizations and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	2-Bromo-3'-Chloro-4'-Fluoroacetophenone, 96%
CAS No.	63529-30-6
Molecular Formula	C8H5BrClFO
Molecular Weight	251.48 g/mol
Synonyms	1-(3-Chloro-4-fluorophenyl)-2-bromoethanone; 2-Bromo-1-(3-chloro-4-fluorophenyl)ethanone; α-Bromo-3-chloro-4-fluoroacetophenone; 3'-Chloro-4'-fluoro-2-bromoacetophenone; 2-Bromo-3-chloro-4-fluoroacetophenone; Ethanone, 2-bromo-1-(3-chloro-4-fluorophenyl)-; Bromo(3-chloro-4-fluorophenyl)methanone (ambiguous, but used)
EINECS	Contact for details

Quality Control

Our 2-Bromo-3'-Chloro-4'-Fluoroacetophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure the 96% minimum purity and identity are met. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 96.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.