Description

(14R)-Grayanotoxane-3β,5,6β,7α,10,14,16-Heptol 7-Propionate CAS NO 63529-01-1 is a highly specific diterpenoid derivative, a key intermediate in advanced organic synthesis and pharmacological research. Its complex, functionalized grayanotoxane skeleton makes it a valuable scaffold for developing novel bioactive compounds. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors seeking to explore structure-activity relationships or synthesize specialized derivatives.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly for neurological or cardiovascular targets.
• Natural Product Analog Synthesis: Used in medicinal chemistry to create analogs of grayanotoxins for biological activity studies.
• Biochemical Research: Employed as a reference standard or probe in studies investigating ion channel modulation and cellular signaling pathways.
• Agrochemical Development: Acts as a starting material for synthesizing new plant protection agents with unique modes of action.
• Academic & R&D Laboratories: Utilized in universities and research institutes for methodological development in complex molecule synthesis.
• Fine Chemical Production: Incorporated into the manufacture of specialty chemicals requiring a sophisticated diterpenoid core structure.

Basic Information

Product Name	(14R)-Grayanotoxane-3β,5,6β,7α,10,14,16-Heptol 7-Propionate
CAS No.	63529-01-1
Molecular Formula	C23H36O8
Molecular Weight	440.53 g/mol
Synonyms	Grayanotoxin III 7-Propionate; (14R)-Grayanotoxane-3,5,6,7,10,14,16-heptol 7-propanoate; 7-O-Propionylgrayanotoxin III; Grayanotoxin III propionate; 3,5,6,7,10,14,16-Heptahydroxygrayanotoxan-7-yl propionate; 14R-Grayanotoxane-3β,5,6β,7α,10,14,16-heptol 7-propanoate
EINECS	Contact for details

Quality Control

Our (14R)-Grayanotoxane-3β,5,6β,7α,10,14,16-Heptol 7-Propionate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets exacting R&D and production standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.