Description

Dichloridophosphoric Acid 4-Methyl-2-Oxo-2H-1-Benzopyran-7-Yl Ester is a specialized organophosphorus derivative of the coumarin scaffold, serving as a critical synthetic intermediate. Its primary value lies in its reactive dichlorophosphoryl group, which enables the efficient introduction of phosphate-like moieties into target molecules under controlled conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced chemical probes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, pesticides, and plant growth regulators.
• Chemical Biology Probe Development: Acts as a versatile precursor for creating activity-based probes to study phosphotransferase and hydrolase enzymes.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific light-absorbing or reactive properties.
• Cross-Coupling & Functionalization Reactions: Serves as an electrophilic phosphorylating agent in organic synthesis to install protected phosphate groups.

Basic Information

Product Name	Dichloridophosphoric Acid 4-Methyl-2-Oxo-2H-1-Benzopyran-7-Yl Ester
CAS No.	63468-52-0
Molecular Formula	C10H7Cl2O4P
Molecular Weight	293.04 g/mol
Synonyms	7-Hydroxy-4-methylcoumarin O,O-Dichlorophosphate; 4-Methylumbelliferone Dichlorophosphate; 4-Methyl-7-hydroxycoumarin Dichlorophosphate; 7-[(Dichlorophosphinyl)oxy]-4-methyl-2H-1-benzopyran-2-one; Coumarin-4-methyl-7-yl Dichlorophosphate; Phosphorodichloridic Acid, 4-Methyl-2-oxo-2H-1-benzopyran-7-yl Ester
EINECS	Contact for details

Quality Control

Every batch of Dichloridophosphoric Acid 4-Methyl-2-Oxo-2H-1-Benzopyran-7-Yl Ester is produced and tested under stringent quality management protocols to ensure consistency and reliability for your critical R&D and scale-up processes. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and strong acid/organic solvent properties, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.