Description

3β,16α,21β-Trihydroxyoleana-12-Ene-28-Oic Acid 28,21-Lactone is a high-purity pentacyclic triterpenoid lactone derivative of oleanolic acid, valued for its role as a critical intermediate in advanced pharmaceutical synthesis and biochemical research. This compound is essential for developing novel therapeutic agents due to its complex, functionalized structure which serves as a versatile scaffold. It is primarily sought by research institutions and manufacturers in the pharmaceutical, biotechnology, and nutraceutical sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel triterpenoid-based drugs targeting inflammation, metabolic disorders, and oncology.
• Biochemical Research: Used as a reference standard and probe in studies investigating triterpenoid biosynthesis, metabolism, and biological activity.
• Natural Product Derivatization: Serves as a starting material for creating semi-synthetic analogs of oleanolic acid with enhanced bioavailability or targeted efficacy.
• High-Purity Analytical Standard: Employed in quality control laboratories for the identification and quantification of triterpenoid compounds via HPLC, LC-MS, or NMR.
• Preclinical Development: Utilized in the early-stage development of new chemical entities (NCEs) for pharmacological and toxicological profiling.

Basic Information

Product Name	3β,16α,21β-Trihydroxyoleana-12-Ene-28-Oic Acid 28,21-Lactone
CAS No.	63432-41-7
Molecular Formula	C30H44O5
Molecular Weight	484.67 g/mol
Synonyms	Oleanolic Acid 28,21-Lactone Derivative; 3β,16α,21β-Trihydroxyolean-12-en-28-oic acid γ-lactone; 3-Epi-16α-Hydroxy-21β-H Oleanolic Acid Lactone; Bayogenin Lactone; 3β,16α,21β-Trihydroxyolean-12-en-28-oic acid 28→21-lactone; (3β,16α,21β)-16,21,28-Trihydroxyolean-12-en-3-yl 2-methylpropanoate (lactone form); 3-Epibayogenin
EINECS	Contact for details

Quality Control

Every batch of 3β,16α,21β-Trihydroxyoleana-12-Ene-28-Oic Acid 28,21-Lactone is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards for identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.