Description

4-(4-Fluorophenyl)Butan-2-One is a versatile fluorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. Its value lies in the strategic incorporation of a fluorine atom and a ketone functional group, enabling precise molecular modifications to enhance the properties of target compounds. This high-purity building block is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, where the fluorine atom can improve bioavailability and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for display technologies.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport or host materials in OLED device fabrication.
• Fine Chemical Research: Employed in academic and industrial R&D for exploring new fluorination reactions and creating complex molecular architectures.
• Polymer Modification: Used to introduce fluorinated phenyl groups into polymer chains to alter thermal and surface properties.

Basic Information

Product Name	4-(4-Fluorophenyl)Butan-2-One
CAS No.	63416-61-5
Molecular Formula	C10H11FO
Molecular Weight	166.19 g/mol
Synonyms	1-(4-Fluorophenyl)-3-butanone; 4'-Fluorobutyrophenone; 4-Fluorophenyl ethyl ketone; p-Fluorobutyrophenone; 3-Oxo-1-(4-fluorophenyl)butane; 4-Fluorobutyrophenone; Butan-2-one, 4-(4-fluorophenyl)-; 1-(p-Fluorophenyl)-3-butanone
EINECS	Contact for details

Quality Control

Our 4-(4-Fluorophenyl)Butan-2-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters to support your quality assurance protocols and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.