Description

Cyclopropanecarboxylic Acid, 1-Amino-2-Ethyl-, (1R,2R)- (9Ci) is a high-purity, chiral cyclopropane derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block for constructing complex molecules with defined stereochemistry, enabling the development of novel active ingredients. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science. The CAS number for this compound is 63393-57-7.

Application

This chiral cyclopropane derivative serves as a key intermediate in the synthesis of complex bioactive molecules. Its primary applications include:

• Pharmaceutical Intermediates: A critical chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the cyclopropane ring and chiral centers contribute to specific biological activity.
• Asymmetric Catalysis Ligand Precursor: The amino and carboxylic acid functionalities make it a potential precursor for chiral ligands and organocatalysts used in enantioselective synthesis.
• Peptidomimetics and Bioisosteres: The constrained cyclopropane ring is valuable in medicinal chemistry for designing peptide mimics and bioisosteric replacements to improve metabolic stability and binding affinity.
• Chemical Research & Development: Employed in academic and industrial R&D settings for methodological studies in stereoselective synthesis and the construction of complex molecular architectures.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-Amino-2-Ethyl-, (1R,2R)- (9Ci)
CAS No.	63393-57-7
Molecular Formula	C6H11NO2
Molecular Weight	129.16 g/mol
Synonyms	(1R,2R)-1-Amino-2-ethylcyclopropanecarboxylic acid; (1R,2R)-1-Amino-2-ethylcyclopropane-1-carboxylic acid; (1R,2R)-2-Ethyl-1-aminocyclopropanecarboxylic acid; trans-1-Amino-2-ethylcyclopropanecarboxylic acid; (1R,2R)-AECC; 1-Amino-2-ethylcyclopropanecarboxylic acid (stereoisomer); Cyclopropanecarboxylic acid, 1-amino-2-ethyl-, (1R,2R)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data to support your R&D and scale-up activities. Certificates of Analysis (COA) are available upon request, detailing parameters such as chiral purity, chemical purity, and identity confirmation. Our quality systems are designed to meet the stringent requirements of pharmaceutical and fine chemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1R,2R)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.