Description

2-Propen-1-One, 1-(2,4-Dichlorophenyl)-2-(1H-Imidazol-1-Yl)-3-Phenyl-, (E)- (9Ci) is a specialized organic compound featuring a unique α,β-unsaturated ketone (enone) structure integrated with imidazole and dichlorophenyl moieties. This molecular architecture makes it a valuable advanced intermediate for the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, where its defined stereochemistry (E-isomer) and functional groups offer precise synthetic handles.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and development of new drug candidates, particularly those targeting fungal infections, given the presence of the imidazole pharmacophore.
• Agrochemical Synthesis: Used in the creation of novel fungicides and pesticides, leveraging its dichlorophenyl and imidazole components for biological activity.
• Chemical Research: Acts as a versatile substrate in organic synthesis for studying Michael addition reactions, cyclization processes, and the development of new heterocyclic compounds.
• Material Science Precursor: Potential use in synthesizing specialized monomers or ligands for advanced polymeric or coordination complex materials.

Basic Information

Product Name	2-Propen-1-One, 1-(2,4-Dichlorophenyl)-2-(1H-Imidazol-1-Yl)-3-Phenyl-, (E)- (9Ci)
CAS No.	63334-76-9
Molecular Formula	C18H12Cl2N2O
Molecular Weight	343.21 g/mol
Synonyms	(E)-1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)-3-phenyl-2-propen-1-one; (E)-2,4-Dichloro-α-(1H-imidazol-1-yl)-β-phenylcinnamaldehyde; 1-(2,4-Dichlorophenyl)-2-(imidazol-1-yl)-3-phenyl-2-propen-1-one (E)-; (E)-1-(2,4-Dichlorophenyl)-2-(imidazol-1-yl)-3-phenylprop-2-en-1-one; α-(1H-Imidazol-1-yl)-2,4-dichloro-β-phenylcinnamaldehyde; NSC 339586; Enone-imidazole derivative 63334-76-9
EINECS	Contact for details

Quality Control

Our production of this high-purity intermediate follows strict quality protocols to ensure batch-to-batch consistency and reliability for critical R&D and scale-up processes. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity, isomeric purity (E-configuration), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Purity (E-Isomer)	≥ 98.0% (by HPLC)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.