Description

(S)-(-)-2-(Methoxymethyl)-1-Pyrrolidinecarboxaldehyde is a high-value chiral building block and organocatalyst precursor. This compound matters for its role in facilitating the synthesis of complex, enantiomerically pure molecules, which is critical in modern pharmaceutical and fine chemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for asymmetric synthesis and catalyst development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system.
• Organocatalyst Precursor: Serves as a starting material for the preparation of various proline-derived organocatalysts used in asymmetric aldol, Michael, and Mannich reactions.
• Asymmetric Synthesis: Employed in the construction of chiral pyrrolidine and piperidine scaffolds, which are common structural motifs in bioactive molecules.
• Agrochemical Research: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process optimization.
• Ligand Synthesis: Utilized for creating chiral ligands for transition metal catalysis.

Basic Information

Product Name	(S)-(-)-2-(Methoxymethyl)-1-Pyrrolidinecarboxaldehyde
CAS No.	63126-45-4
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(S)-(-)-2-(Methoxymethyl)pyrrolidine-1-carbaldehyde; (S)-N-Formyl-2-(methoxymethyl)pyrrolidine; L-Proline, 2-(methoxymethyl)-, aldehyde; (S)-2-(Methoxymethyl)-1-formylpyrrolidine; (S)-1-Formyl-2-(methoxymethyl)pyrrolidine; (2S)-2-(Methoxymethyl)-1-pyrrolidinecarboxaldehyde; (S)-(-)-N-Formyl-2-(methoxymethyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our (S)-(-)-2-(Methoxymethyl)-1-Pyrrolidinecarboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.