Description

2,2-Di-(Prop-2-Ynyl)-Malonic Acid Dimethyl Ester is a specialized diester derivative of malonic acid, featuring two propargyl (prop-2-ynyl) groups. This compound serves as a valuable high-purity synthetic intermediate and building block in advanced organic synthesis. It is primarily utilized by pharmaceutical R&D and fine chemical industries for constructing complex molecular architectures, including heterocycles and functionalized polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Click Chemistry Reagent: Utilized in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions due to its terminal alkyne functionality.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for the production of specialty polymers and resins.
• Organic Synthesis: Used in Michael additions, alkylations, and other C-C bond-forming reactions to create complex organic molecules.
• Agrochemical Research: Intermediate in the development of new pesticides and herbicides.
• Material Science: Precursor for advanced materials, including coatings and adhesives with tailored properties.

Basic Information

Product Name	2,2-Di-(Prop-2-Ynyl)-Malonic Acid Dimethyl Ester
CAS No.	63104-44-9
Molecular Formula	C11H12O4
Molecular Weight	208.21 g/mol
Synonyms	Dimethyl 2,2-bis(prop-2-yn-1-yl)malonate; Dimethyl 2,2-Dipropargylmalonate; 2,2-Bis(2-Propynyl)malonic Acid Dimethyl Ester; Malonic Acid, 2,2-Bis(2-propynyl)-, Dimethyl Ester; Propargylmalonic Acid Dimethyl Ester; Dipropargylmalonic Acid Dimethyl Ester
EINECS	Contact for details

Quality Control

Our 2,2-Di-(Prop-2-Ynyl)-Malonic Acid Dimethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.