Description

4-Chloropicolinaldehyde is a versatile halogenated heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both an aldehyde group and a chlorinated pyridine ring, makes it a critical intermediate for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key precursor for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key starting material in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging its reactive aldehyde and halogen sites.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of functional organic materials, such as liquid crystals and organic semiconductors.
• Cross-Coupling Reactions: The chloro substituent makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck).
• Chemical Derivatization: The aldehyde group is readily available for condensation reactions (e.g., formation of imines, hydrazones) to create diverse chemical libraries.

Basic Information

Product Name	4-Chloropicolinaldehyde
CAS No.	63071-13-6
Molecular Formula	C6H4ClNO
Molecular Weight	141.56 g/mol
Synonyms	4-Chloro-2-pyridinecarboxaldehyde; 4-Chloropyridine-2-carbaldehyde; 2-Pyridinecarboxaldehyde, 4-chloro-; 4-Chloro-2-formylpyridine; 4-Chloropicolinaldehyde; Picolinaldehyde, 4-chloro-
EINECS	Contact for details

Quality Control

Our 4-Chloropicolinaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.