Description

(3As)-3Aβ,4,4A,5,6,7,8,9Aβ-Octahydro-4Aβ,5β-Dimethyl-3-Methylenenaphtho[2,3-B]Furan-2(3H)-One is a high-purity, complex sesquiterpene lactone derivative with a unique fused furanone structure. This compound is a critical advanced pharmaceutical intermediate and a versatile building block for organic synthesis, valued for its stereochemical complexity and functional groups. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug candidates, particularly in oncology and anti-inflammatory research.
• Agrochemical Synthesis: Used as a core scaffold for developing novel, high-performance pesticides and herbicides with specific modes of action.
• Fine Chemical Building Block: Employed in asymmetric synthesis and total synthesis projects to construct intricate natural product analogs.
• Flavor & Fragrance Ingredient: Serves as a starting material for synthesizing unique sesquiterpenoid-based aroma chemicals.
• Academic & Industrial Research: A valuable reference standard and reagent for methodological studies in organic chemistry and catalysis.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with tailored properties.

Basic Information

Item	Details
Product Name	(3As)-3Aβ,4,4A,5,6,7,8,9Aβ-Octahydro-4Aβ,5β-Dimethyl-3-Methylenenaphtho[2,3-B]Furan-2(3H)-One
CAS No.	62870-69-3
Molecular Formula	C15H20O2
Molecular Weight	232.32 g/mol
Synonyms	3-Methylenenaphtho[2,3-b]furan-2(3H)-one, octahydro-4aβ,5β-dimethyl-, (3aS,4S,4aR,5S,9aR)-; Alantolactone isomer; Isoalantolactone (related); Helenin (constituent); Inula helenium lactone derivative; (3aS,4S,4aR,5S,9aR)-4a,5-Dimethyl-3-methylidene-3a,4,4a,5,6,7,8,9a-octahydronaphtho[2,3-b]furan-2-one
EINECS	Contact for details

Quality Control

Our production of (3As)-3Aβ,4,4A,5,6,7,8,9Aβ-Octahydro-4Aβ,5β-Dimethyl-3-Methylenenaphtho[2,3-B]Furan-2(3H)-One adheres to stringent in-process controls and final release testing. We guarantee high batch-to-batch consistency and purity suitable for demanding synthetic applications. All products undergo rigorous quality testing, including chiral purity analysis, to ensure compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to atmospheric moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.