Description

1-Ethynyl-1-(Trimethylsiloxy)Cyclohexane is a versatile organosilicon compound featuring both an ethynyl and a trimethylsiloxy functional group on the same carbon atom. This unique structure makes it a valuable protected acetylene synthon and a key building block in advanced organic synthesis. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical and specialty chemical industries for constructing complex molecular architectures, including natural products and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules and bioactive compounds.
• Advanced Organic Synthesis: Serves as a protected acetylene equivalent for Sonogashira coupling and other cross-coupling reactions.
• Material Science Research: Used in the development of novel polymers and silicon-containing advanced materials.
• Agrochemical Synthesis: Employed as a building block for creating new crop protection agents and herbicides.
• Academic & Industrial R&D: A valuable reagent for methodology development and exploring new chemical spaces in laboratory settings.

Basic Information

Product Name	1-Ethynyl-1-(Trimethylsiloxy)Cyclohexane
CAS No.	62785-90-4
Molecular Formula	C11H20OSi
Molecular Weight	196.36 g/mol
Synonyms	1-(Trimethylsiloxy)-1-ethynylcyclohexane; 1-Ethynyl-1-(trimethylsilyloxy)cyclohexane; Cyclohexane, 1-ethynyl-1-[(trimethylsilyl)oxy]-; (1-Ethynylcyclohexyloxy)trimethylsilane; TMS-protected ethynylcyclohexanol; 1-[(Trimethylsilyl)oxy]-1-ethynylcyclohexane
EINECS	Contact for details

Quality Control

Our production of 1-Ethynyl-1-(Trimethylsiloxy)Cyclohexane adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability. Each lot is characterized using advanced analytical techniques including GC, HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and highly volatile nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.