Description

3-(Dimethylamino)-2-[3-(Trifluoromethyl)Phenyl]Acrylonitrile is a specialized acrylonitrile derivative featuring a trifluoromethylphenyl group, making it a valuable fluorinated building block in advanced organic synthesis. This compound is particularly significant for its role in the development of pharmaceuticals and agrochemicals, where the introduction of fluorine atoms is crucial for modulating biological activity, metabolic stability, and lipophilicity. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances efficacy and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced functional materials with unique optical or electronic properties.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis and metal-organic frameworks (MOFs) due to its electron-withdrawing and steric properties.
• Fluorine Chemistry Studies: An important reagent for academic and industrial research focused on incorporating fluorinated motifs into organic molecules.
• Dye and Pigment Intermediate: Can be utilized in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	3-(Dimethylamino)-2-[3-(Trifluoromethyl)Phenyl]Acrylonitrile
CAS No.	62738-99-2
Molecular Formula	C₁₂H₁₁F₃N₂
Molecular Weight	240.23 g/mol
Synonyms	2-[3-(Trifluoromethyl)phenyl]-3-(dimethylamino)acrylonitrile; 3-(Dimethylamino)-2-(3-trifluoromethylphenyl)propenenitrile; (E/Z)-3-(Dimethylamino)-2-[3-(trifluoromethyl)phenyl]acrylonitrile; α-Cyano-β-dimethylamino-3-(trifluoromethyl)styrene; 3-(N,N-Dimethylamino)-2-(3-trifluoromethylphenyl)acrylonitrile; 62738-99-2; 3-(Dimethylamino)-2-(3-trifluoromethylphenyl)-2-propenenitrile
EINECS	Contact for details

Quality Control

Our 3-(Dimethylamino)-2-[3-(Trifluoromethyl)Phenyl]Acrylonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and commercial-scale synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.