Description

4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)benzoic acid is a valuable benzoic acid derivative containing a pinacol boronate ester functional group. This compound serves as a crucial synthetic intermediate and building block in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: As a key aryl boronate ester reagent for forming carbon-carbon bonds in medicinal chemistry and materials science.
• Pharmaceutical Intermediate: In the research and synthesis of novel drug candidates, especially those requiring biaryl or substituted benzoic acid motifs.
• Agrochemical Synthesis: As a building block for creating new herbicides, fungicides, and insecticides with enhanced properties.
• Ligand and Catalyst Development: For the preparation of specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: In the development of organic electronic materials, polymers, and liquid crystals.
• Chemical Biology Probes: For labeling and modifying biomolecules in proteomics and diagnostic assay development.

Basic Information

Item	Detail
Product Name	4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)benzoic Acid
CAS No.	62729-39-9
Molecular Formula	C13H17BO4
Molecular Weight	248.09 g/mol
Synonyms	4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)benzoic acid; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid (common misassignment); 4-Bpin-benzoic acid; 4-Carboxyphenylboronic acid pinacol ester; Benzoic acid, 4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-; 4-(Pinacolatoboryl)benzoic acid; 4-Boronobenzoic acid pinacol cyclic ester; p-Carboxybenzeneboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)benzoic acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance as a synthetic reagent. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of research and development and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.