Description

3-Hydroxy-2-Iodobenzaldehyde is a versatile halogenated aromatic aldehyde building block of significant interest in advanced organic synthesis. Its unique structure, featuring both an aldehyde group and a phenolic hydroxyl group ortho to an iodine atom, makes it a critical precursor for constructing complex molecular architectures. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Precursor: Serves as a foundational unit for creating sophisticated chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and metal-organic frameworks (MOFs) due to its functional handle for polymerization and coordination.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and protein labeling.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl and other conjugated systems.

Basic Information

Product Name	3-Hydroxy-2-Iodobenzaldehyde
CAS No.	62672-58-6
Molecular Formula	C7H5IO2
Molecular Weight	248.02 g/mol
Synonyms	2-Iodo-3-hydroxybenzaldehyde; 3-Hydroxy-2-iodobenzenecarboxaldehyde; 2-Iodosalicylaldehyde; Salicylaldehyde, 2-iodo-; 3-Hydroxy-2-iodo-benzaldehyde; Benzaldehyde, 3-hydroxy-2-iodo-; 2-Iodo-3-hydroxy-benzaldehyde
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-2-Iodobenzaldehyde is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to confirm identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP and ISO compliant manufacturing for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.