Description

1-Bromo-3-Methanesulfonyl-5-Nitrobenzene is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. Its unique combination of bromo, methanesulfonyl, and nitro substituents makes it a versatile intermediate for constructing complex molecular architectures. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key precursor in the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting specific receptors or enzymes.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations.
• Nucleophilic Aromatic Substitution: The electron-deficient nitro group activates the ring for substitution reactions, enabling further functionalization.
• Dye and Pigment Intermediate: Used in the synthesis of complex organic dyes and pigments due to its stable aromatic core and modifiable functional groups.

Basic Information

Product Name	1-Bromo-3-Methanesulfonyl-5-Nitrobenzene
CAS No.	62606-15-9
Molecular Formula	C7H6BrNO4S
Molecular Weight	280.10 g/mol
Synonyms	3-Bromo-5-Nitrobenzenesulfonyl Methane; 1-Bromo-3-(Methylsulfonyl)-5-Nitrobenzene; 5-Bromo-1-Methanesulfonyl-3-Nitrobenzene; 3-Bromo-5-Nitrophenyl Methyl Sulfone; Benzene, 1-bromo-3-(methylsulfonyl)-5-nitro-; Methyl 3-Bromo-5-Nitrophenyl Sulfone
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Methanesulfonyl-5-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage to maintain stability and purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.