Description

Rel-(1-Methylethyl)Phenylphosphinous Acid (1S*)-2β*-(1-Methylethyl)-5α*-Methylcyclohexane-1α*-Yl Ester is a specialized organophosphorus compound featuring a chiral, sterically hindered structure. This compound matters as a high-value intermediate or ligand in advanced chemical synthesis, where its unique stereochemistry and phosphorus center enable precise control over reaction pathways. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for applications such as asymmetric catalysis and the development of novel active ingredients.

Application

• Asymmetric Catalysis: Serving as a chiral ligand or precursor for transition metal catalysts in stereoselective synthesis.
• Pharmaceutical Intermediates: A key building block in the synthesis of complex, biologically active molecules requiring specific stereochemistry.
• Agrochemical Research: Used in the development of novel herbicides, insecticides, or fungicides with targeted modes of action.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, flavors, and fragrances where precise molecular architecture is critical.
• Material Science: Potential application as a modifier or additive in advanced polymeric materials.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic and organometallic chemistry.

Basic Information

Product Name	Rel-(1-Methylethyl)Phenylphosphinous Acid (1S*)-2β*-(1-Methylethyl)-5α*-Methylcyclohexane-1α*-Yl Ester
CAS No.	62376-13-0
Molecular Formula	C19H31OP
Molecular Weight	306.43 g/mol
Synonyms	(1S*,2R*,5R*)-2-Isopropyl-5-methylcyclohexyl isopropyl(phenyl)phosphinite; Isopropyl(phenyl)phosphinous Acid (1S*,2R*,5R*)-2-Isopropyl-5-methylcyclohexyl Ester; Menthol-Derived Isopropylphenylphosphinite; Chiral Isopropylphenylphosphinite Ester; (1R,2S,5R)-Menthyl Isopropyl(Phenyl)Phosphinite; Sterically Hindered Phosphinite Ligand; CAS 62376-13-0
EINECS	Contact for details

Quality Control

Our production of this high-purity organophosphorus intermediate adheres to strict quality protocols. Every batch undergoes comprehensive analysis, including chiral purity assessment by HPLC and structural confirmation by NMR and IR spectroscopy, to ensure it meets the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, enantiomeric/excess, and key physical parameters.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being easily oxidized (store under inert atmosphere) and hygroscopic (moisture-sensitive), it is recommended to store the material under an inert gas (e.g., nitrogen or argon) in a cool, dry place. For long-term stability, storage at 2-8°C is advised. Keep away from strong oxidizers and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.