Description

1,3-Bis(4-fluorophenyl)-3-hydroxy-2-propan-1-one (CAS 62375-96-6) is a high-purity fluorinated aromatic ketone intermediate of significant commercial interest. This compound serves as a critical building block in advanced organic synthesis, valued for its unique molecular structure that incorporates both ketone and hydroxyl functional groups flanked by fluorinated aromatic rings. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a core component in the development of fluorinated liquid crystals for high-performance displays (LCDs) due to its dipolar structure and stability.
• Organic Light-Emitting Diodes (OLEDs): Employed as a building block for electron-transport materials or host materials in OLED device fabrication.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with enhanced thermal and chemical resistance.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry and material science R&D for structure-activity relationship (SAR) studies and novel compound libraries.

Basic Information

Product Name	1,3-Bis(4-fluorophenyl)-3-hydroxy-2-propan-1-one
CAS No.	62375-96-6
Molecular Formula	C15H12F2O2
Molecular Weight	274.25 g/mol
Synonyms	1,3-Bis(p-fluorophenyl)-3-hydroxy-1-propanone; 3-Hydroxy-1,3-bis(4-fluorophenyl)propan-1-one; 3-Hydroxy-1,3-di(4-fluorophenyl)-1-propanone; 1-Propanone, 1,3-bis(4-fluorophenyl)-3-hydroxy-; 62375-96-6; 1,3-Di(4-fluorophenyl)-3-hydroxypropan-1-one
EINECS	Contact for details

Quality Control

Our production of 1,3-Bis(4-fluorophenyl)-3-hydroxy-2-propan-1-one adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assay and identity confirmation via FT-IR and NMR spectroscopy, to ensure consistency and meet exacting customer specifications. Certificates of Analysis (COA) detailing all test parameters and results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.