Description

(4R,4'S)-2,2'-Diethyl-4,4'-Bi[1,3,2-Dioxaborolane] is a chiral, non-racemic organoboron reagent of significant synthetic utility. This compound matters for its role as a key intermediate in asymmetric synthesis, particularly in the formation of carbon-boron bonds for subsequent cross-coupling reactions. It is primarily needed by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing complex, stereodefined molecular architectures.

Application

• Asymmetric Suzuki-Miyaura Cross-Coupling: A crucial chiral ligand or precursor for palladium-catalyzed cross-couplings to form stereogenic centers.
• Pharmaceutical Intermediate Synthesis: Used in the production of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Chiral Auxiliary or Catalyst Preparation: Serves as a building block for more complex chiral ligands used in catalysis.
• Organic Light-Emitting Diode (OLED) Materials Research: Employed in the synthesis of chiral, boron-containing molecules for optoelectronic applications.
• Academic & Industrial R&D: A valuable tool for methodological development in organic and organometallic chemistry.
• Synthesis of Boronic Esters and Acids: Acts as a protected, chiral form of a diboronic species for sequential functionalization.

Basic Information

Product Name	(4R,4'S)-2,2'-Diethyl-4,4'-Bi[1,3,2-Dioxaborolane]
CAS No.	62337-94-4
Molecular Formula	C10H18B2O4
Molecular Weight	239.87 g/mol
Synonyms	(4R,4'S)-2,2'-Diethyl-4,4'-bi-1,3,2-dioxaborolane; (R,R)-2,2'-Diethyl-4,4'-bi(1,3,2-dioxaborolane); (4R,4'S)-Diethyl-4,4'-bidioxaborolane; Chiral Diethyl Dioxaborolane Dimer; (R,R)-Diethylbis(dioxaborolane); 4,4'-Bi(1,3,2-dioxaborolane), 2,2'-diethyl-, (4R,4'S)-; (4R,4'S)-2,2'-Diethyl-4,4'-bis(1,3,2-dioxaborolane)
EINECS	Contact for details

Quality Control

Our (4R,4'S)-2,2'-Diethyl-4,4'-Bi[1,3,2-Dioxaborolane] is manufactured under strict quality protocols to ensure high chiral purity and chemical integrity, suitable for sensitive synthetic applications. Each batch is characterized by NMR, HPLC, and optical rotation analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) with full analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic nature, containers should be sealed under an inert atmosphere (argon or nitrogen) after opening and kept in a desiccator to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.