Description

(1R,8Aα)-Decahydro-8α-Hydroxymethyl-3,4Aβ,8-Trimethyl-4β-(3-Methylene-4-Pentenyl)-1α,3α-Naphthalenediol is a complex, high-purity diterpenoid derivative with a unique stereochemical framework. This compound serves as a critical advanced intermediate for the synthesis of novel bioactive molecules, offering researchers a sophisticated building block with multiple functional handles. It is primarily sought by pharmaceutical R&D and fine chemical synthesis teams working on complex natural product analogs and therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the research and development of novel drug candidates, particularly in oncology and anti-inflammatory therapeutic areas.
• Natural Product Synthesis: Used in the total or semi-synthesis of complex diterpenoid natural products and their structural analogs for biological evaluation.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies due to its multiple stereocenters and functional groups.
• Chemical Biology Probes: Employed in the development of molecular probes to study enzyme mechanisms and biological pathways.
• High-Value Fine Chemical Production: An essential intermediate in multi-step synthetic routes for producing specialized, low-volume, high-value chemicals.
• Academic Research: Utilized in university and institutional laboratories for advanced organic synthesis projects and methodology development.

Basic Information

Product Name	(1R,8Aα)-Decahydro-8α-Hydroxymethyl-3,4Aβ,8-Trimethyl-4β-(3-Methylene-4-Pentenyl)-1α,3α-Naphthalenediol
CAS No.	62279-93-0
Molecular Formula	C22H38O3
Molecular Weight	350.54 g/mol
Synonyms	8α-Hydroxymethyl-3,4aβ,8-trimethyl-4β-(3-methylene-4-pentenyl)decahydro-1α,3α-naphthalenediol; (1R,4aR,4bR,8aR,9S,10aR)-9-(Hydroxymethyl)-1,4a,7-trimethyl-6-methylene-2,3,4,4a,4b,5,8,8a,9,10-decahydro-1H-phenanthrene-1,3-diol; Diterpenoid Diol Derivative; CAS 62279-93-0
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.