Description

Dimethyl-(1-Methylacetonyl)Phosphonate is a specialized organophosphorus compound with a reactive β-ketophosphonate structure. This chemical serves as a versatile building block in organic synthesis, enabling the formation of complex molecular frameworks. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing key intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing phosphorus or complex ketone functionalities.
• Agrochemical Synthesis: Used in the production of advanced herbicides, insecticides, and plant growth regulators that require specific phosphonate ester groups.
• Ligand and Catalyst Development: Serves as a starting material for creating novel phosphorus-containing ligands used in transition metal catalysis.
• Material Science Research: Employed in the development of flame retardants, plasticizers, and specialty polymers where phosphonate groups enhance material properties.
• Organic Synthesis Reagent: Functions as a reagent in Horner-Wadsworth-Emmons (HWE) olefination reactions to generate α,β-unsaturated carbonyl compounds.
• Chemical Research & Development: A valuable tool for medicinal chemistry and process chemistry R&D for exploring new synthetic routes and molecular entities.

Basic Information

Product Name	Dimethyl-(1-Methylacetonyl)Phosphonate
CAS No.	62269-22-1
Molecular Formula	C6H13O4P
Molecular Weight	180.14 g/mol
Synonyms	Dimethyl (1-methyl-2-oxopropyl)phosphonate; Dimethyl (2-oxobutyl)phosphonate; 1-Methylacetonylphosphonic Acid Dimethyl Ester; 2-Oxobutylphosphonic Acid Dimethyl Ester; (1-Methyl-2-oxopropyl)phosphonic Acid Dimethyl Ester; Acetylpropionylphosphonate Dimethyl Ester; DMAPO (abbreviation)
EINECS	Contact for details

Quality Control

Our Dimethyl-(1-Methylacetonyl)Phosphonate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.15 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.