Description

3-Deoxyryanodol 10-Acetate is a high-purity, semi-synthetic derivative of the complex diterpenoid natural product ryanodol. This compound serves as a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies focused on neurobiology, insecticide development, and calcium channel modulation studies.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel ryanodine receptor (RyR) modulators and related therapeutic agents.
• Biochemical Research: Used as a reference standard and tool compound in studies investigating calcium release channel mechanics and intracellular signaling pathways.
• Agrochemical Research: Serves as a structural template and intermediate in the development of next-generation, selective insecticidal compounds targeting the ryanodine receptor in pests.
• Analytical Standard: Employed in HPLC, LC-MS, and NMR for method development, calibration, and quantification in complex biological or chemical matrices.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies aimed at optimizing potency and selectivity for specific RyR isoforms.

Basic Information

Product Name	3-Deoxyryanodol 10-Acetate
CAS No.	62203-47-8
Molecular Formula	C22H32O7
Molecular Weight	408.49 g/mol
Synonyms	10-Acetoxy-3-deoxyryanodol; 3-Deoxy-10-O-acetylryanodol; Ryanodol, 3-deoxy-, 10-acetate; 3-Deoxyryanodol acetate; (1R,2S,3S,6S,7S,8S,9R,11S,12S,14S,15R)-6-(Acetyloxy)-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydro-7,14-dihydroxy-1,3:8,12-diepoxy-7,9-methano-11,15-methano-2H-6,10a-[1,2]benzenodioxacyclotetradecin-2-one
EINECS	Contact for details

Quality Control

Our 3-Deoxyryanodol 10-Acetate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.