Description

4-Chloro-3-(trifluoromethyl)benzylamine is a high-value, multi-functional aromatic amine building block characterized by its chloro and trifluoromethyl substituents. This compound is essential for synthesizing advanced molecules where its unique halogenated and fluorinated structure imparts critical properties like metabolic stability, lipophilicity, and bioactivity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the CF3 group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Incorporated into the synthesis of specialty polymers, liquid crystals, and advanced organic frameworks (MOFs/COFs).
• Fluorinated Compound Research: A valuable starting material in academic and industrial R&D for exploring structure-activity relationships (SAR) in fluorochemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke, high-value chemical entities under cGMP or research-grade conditions.

Basic Information

Product Name	4-Chloro-3-(trifluoromethyl)benzylamine
CAS No.	62039-92-3
Molecular Formula	C8H7ClF3N
Molecular Weight	209.60 g/mol
Synonyms	1-(4-Chloro-3-(trifluoromethyl)phenyl)methanamine; (4-Chloro-3-(trifluoromethyl)phenyl)methanamine; α-Amino-4-chloro-alpha,alpha,α-trifluoro-m-xylene; 4-Chloro-3-trifluoromethylbenzylamine; 4-Chloro-alpha,alpha,α-trifluoro-m-toluidine; 4-Chloro-3-(trifluoromethyl)benzenemethanamine; 62039-92-3; 4-Chloro-3-trifluoromethyl benzylamine
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-(trifluoromethyl)benzylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent composition. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring research-grade to cGMP-compliant materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This amine is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.