Description

4'-Chloro-5-Hydroxy-(1,1'-Biphenyl)-3-Acetic Acid Ethyl Ester is a specialized biphenyl derivative ester, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both phenolic and ester functional groups on a chlorinated biphenyl scaffold, makes it a valuable building block for constructing complex molecules. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules targeting inflammation and pain.
• Agrochemical Research: Used as a building block for developing new herbicides and fungicides, leveraging the biphenyl core for biological activity.
• Material Science: Serves as a monomer or cross-linking agent in the research and development of specialized polymers and liquid crystals.
• Organic Synthesis: A versatile reagent for constructing complex aromatic systems, particularly in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	4'-Chloro-5-Hydroxy-(1,1'-Biphenyl)-3-Acetic Acid Ethyl Ester
CAS No.	61888-75-3
Molecular Formula	C₁₆H₁₅ClO₃
Molecular Weight	290.74 g/mol
Synonyms	Ethyl 4'-Chloro-5-hydroxybiphenyl-3-acetate; 3-(4-Chlorophenyl)-5-hydroxybenzeneacetic Acid Ethyl Ester; 5-Hydroxy-4'-chlorobiphenyl-3-acetic Acid Ethyl Ester; 4'-Chloro-5-hydroxy[1,1'-biphenyl]-3-acetic Acid Ethyl Ester; 4'-Chloro-5-hydroxybiphenyl-3-yl-acetic Acid Ethyl Ester; Ethyl (4'-Chloro-5-hydroxybiphenyl-3-yl)acetate; Biphenyl-3-acetic acid, 4'-chloro-5-hydroxy-, ethyl ester
EINECS	Contact for details

Quality Control

Our 4'-Chloro-5-Hydroxy-(1,1'-Biphenyl)-3-Acetic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.