Description

4'-Chloro-5-Methoxy-3-Biphenylpropionic Acid is a high-purity, non-steroidal anti-inflammatory drug (NSAID) intermediate of significant commercial and research interest. This compound is valued for its role as a key synthetic precursor in the development of advanced pharmaceutical actives. It is primarily sought by manufacturers and R&D laboratories in the pharmaceutical, fine chemical, and life science sectors for process development and active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel NSAIDs and other therapeutic agents.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and new drug candidate development.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex biphenyl-based molecules in custom synthesis projects.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Utilized in studies targeting cyclooxygenase (COX) enzyme pathways and inflammatory processes.

Basic Information

Product Name	4'-Chloro-5-Methoxy-3-Biphenylpropionic Acid
CAS No.	61888-68-4
Molecular Formula	C₁₆H₁₅ClO₃
Molecular Weight	290.74 g/mol
Synonyms	3-(4'-Chloro-5-methoxybiphenyl-3-yl)propanoic acid; 3-(4-Chloro-5-methoxy-3-biphenylyl)propionic Acid; 4'-Chloro-5-methoxy-[1,1'-biphenyl]-3-propanoic Acid; 4'-Chloro-5-methoxybiphenyl-3-propionic Acid; 4'-Chloro-5-methoxy-3-biphenylpropanoic Acid; 61888-68-4; 4-Chloro-5-methoxy-3-biphenylpropionic Acid
EINECS	Contact for details

Quality Control

Our 4'-Chloro-5-Methoxy-3-Biphenylpropionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.