Description

4-Chloro-2-(Trifluoromethyl)Benzenediazonium is a specialized diazonium salt intermediate of significant importance in advanced organic synthesis. Its core value lies in enabling efficient and selective aromatic functionalization, particularly through Sandmeyer and related coupling reactions, which are pivotal for constructing complex molecular architectures. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries, where it serves as a key building block for introducing the chlorotrifluoromethylphenyl moiety.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing trifluoromethyl and chloro substituents for enhanced bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where the chlorotrifluoromethylphenyl group contributes to product efficacy and environmental persistence.
• Dye and Pigment Manufacturing: Serves as a diazo component for producing azo dyes and pigments with specific color fastness and chemical resistance properties.
• Liquid Crystal & OLED Materials: Acts as a building block for synthesizing advanced organic electronic materials that require precise halogenated and fluorinated aromatic structures.
• Polymer Modification: Employed to introduce functional aromatic groups into polymer chains, altering physical properties like thermal stability and solubility.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Heck, Suzuki) for creating biaryl systems common in many specialty chemicals.

Basic Information

Product Name	4-Chloro-2-(Trifluoromethyl)Benzenediazonium
CAS No.	61886-21-3
Molecular Formula	C7H3ClF3N2+ (typically as a salt, e.g., tetrafluoroborate)
Molecular Weight	Contact for details (varies by counterion)
Synonyms	4-Chloro-2-(trifluoromethyl)benzenediazonium salt; 2-Trifluoromethyl-4-chlorobenzenediazonium; 4-Chloro-α,α,α-trifluoro-o-toluenediazonium; Diazonium, [4-chloro-2-(trifluoromethyl)phenyl]-; o-Chloro-α,α,α-trifluorotoluenediazonium; Benzenediazonium, 4-chloro-2-(trifluoromethyl)-; 61886-21-3 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(Trifluoromethyl)Benzenediazonium is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing key parameters such as assay (by HPLC or titration), counterion content, and impurity profile are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at temperatures typically between 2°C and 8°C (refrigerated) or as specified on the label. Due to its nature as a diazonium salt, it should be stored separately from incompatible materials and handled with appropriate precautions to avoid decomposition. Keep container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0% (or as per grade)
Counterion Content	As specified (e.g., BF4-, Cl-, etc.)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Solubility	Soluble in polar aprotic solvents (e.g., DMF, acetonitrile)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.