Description

2-Bromo-m-Iodoacetophenone is a versatile and highly functionalized aromatic ketone derivative, serving as a critical bifunctional building block in advanced organic synthesis. Its value lies in the presence of two distinct halogen substituents (bromine and iodine) on the acetophenone core, which offer orthogonal reactivity for sequential cross-coupling and substitution reactions. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require precise molecular scaffolds for constructing complex heterocycles and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for constructing complex molecular architectures via Suzuki, Stille, or other palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the halogenated acetophenone moiety is incorporated into bioactive molecules.
• Material Science: Acts as a monomer or functionalization agent in the synthesis of specialty polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create tagged molecules or affinity labels for studying biological pathways and protein interactions.
• Academic & R&D Laboratories: Serves as a standard reagent for methodological development in organic chemistry, exploring new halogenation and functional group transformation strategies.
• Ligand Synthesis: Intermediate for preparing sophisticated chelating ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Bromo-m-Iodoacetophenone
CAS No.	61858-38-6
Molecular Formula	C8H6BrIO
Molecular Weight	324.94 g/mol
Synonyms	1-(2-Bromo-3-iodophenyl)ethan-1-one; 2'-Bromo-3'-iodoacetophenone; 1-Acetyl-2-bromo-3-iodobenzene; m-Iodo-2-bromoacetophenone; 3-Iodo-2-bromoacetophenone; α-Bromo-m-iodoacetophenone; (2-Bromo-3-iodophenyl)methyl ketone
EINECS	Contact for details

Quality Control

Our 2-Bromo-m-Iodoacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Solubility	Soluble in common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.