Description

(S)-4-Bromo-1,2-Epoxybutane is a high-value chiral epoxide building block, essential for the synthesis of complex, optically active molecules. Its unique structure, featuring both an epoxide ring and a bromoalkyl chain, makes it a versatile electrophile for nucleophilic ring-opening reactions and subsequent functionalization. This compound is critically needed by pharmaceutical R&D and fine chemical synthesis teams for developing active pharmaceutical ingredients (APIs), chiral ligands, and advanced material precursors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of β-blockers, antiviral agents, and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators requiring specific stereochemistry.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral phosphine ligands, salen complexes, and other organocatalysts.
• Material Science: Employed in the creation of chiral polymers, liquid crystals, and functionalized surfaces with specific optical properties.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules to study protein function and cellular pathways.
• Academic & Industrial Research: A valuable tool for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	(S)-4-Bromo-1,2-Epoxybutane
CAS No.	61847-07-2
Molecular Formula	C4H7BrO
Molecular Weight	151.00 g/mol
Synonyms	(S)-(-)-4-Bromo-1,2-epoxybutane; (S)-1-Bromo-3,4-epoxybutane; (2S)-2-[(2-Bromoethyl)oxirane]; (S)-4-Bromo-1,2-butylene oxide; (S)-Epibromohydrin derivative; (S)-1,2-Epoxy-4-bromobutane; (S)-Glycidyl bromide homologue
EINECS	Contact for details

Quality Control

Our (S)-4-Bromo-1,2-Epoxybutane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and optical purity. Certificates of Analysis (COA) detailing specific results for assay, enantiomeric excess, and impurities are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents and amines. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.