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2-Isopropoxy-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 61676-62-8


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CAS No.:61676-62-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Isopropoxy-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, versatile boronic ester reagent widely used in advanced organic synthesis. Its primary value lies in its stability and reactivity as a key building block for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for drug discovery, catalyst development, and functional polymer synthesis.

Application

  • Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
  • Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific aryl-aryl bond formations.
  • Materials Science & OLED Development: Serves as a key monomer for creating conjugated polymers and organic light-emitting diode (OLED) materials with tailored electronic properties.
  • Ligand & Catalyst Preparation: Employed in the synthesis of sophisticated ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
  • Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new carbon-boron and carbon-carbon bond-forming methodologies.
  • Polymer Chemistry: Utilized to introduce boronate ester functional groups into polymer backbones for creating stimuli-responsive or self-healing materials.

Basic Information

Item Details
Product Name 2-Isopropoxy-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No. 61676-62-8
Molecular Formula C9H19BO3
Molecular Weight 186.06 g/mol
Synonyms Isopropyl Pinacol Boronate; 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Isopropoxy Pinacolborane; Pinacol Isopropyl Boronate; Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; IPBpin; (Isopropoxy)(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)borane
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Quality Control

Our 2-Isopropoxy-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including NMR, GC, and HPLC analysis, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and highly volatile nature, this product must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item Specification
Appearance Colorless to pale yellow clear liquid
Identification (IR) Conforms to structure
Assay (GC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Related Substances (GC) Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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