Description

Chloromethyl Isobutyrate CAS NO 61644-18-6 is a versatile organic ester compound featuring a reactive chloromethyl group. This bifunctional molecule is a critical intermediate in organic synthesis, valued for its ability to introduce both ester and chloromethyl functionalities in a single step. It is primarily sought by manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the production of active ingredients, fine chemicals, and polymer modifiers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring ester or chloromethyl ether linkages.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and plant growth regulators where its reactive groups facilitate structural diversification.
• Polymer & Resin Modifier: Serves as a cross-linking agent or functional monomer to impart specific properties like adhesion, hardness, or chemical resistance to polymers and coatings.
• Fine Chemical Production: Employed in multi-step organic synthesis to construct complex molecules for research, flavors, and fragrances.
• Chemical Derivatization: Useful for protecting groups or as a reagent to introduce the chloromethyl moiety into target molecules in laboratory and industrial settings.

Basic Information

Product Name	Chloromethyl Isobutyrate
CAS No.	61644-18-6
Molecular Formula	C6H11ClO2
Molecular Weight	150.60 g/mol
Synonyms	Isobutyric Acid Chloromethyl Ester; Chloromethyl 2-Methylpropanoate; 2-Methylpropanoic Acid Chloromethyl Ester; (Chloromethoxy)-2-methylpropan-2-one (common misnomer); Isobutyryloxymethyl Chloride; CMI (abbreviation)
EINECS	Contact for details

Quality Control

Our Chloromethyl Isobutyrate is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing, including Gas Chromatography (GC) and Nuclear Magnetic Resonance (NMR), to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Due to its nature as a strong acid/organic solvent, ensure containers are kept tightly sealed to prevent moisture ingress and volatility.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.08 g/cm³
Refractive Index (n20D)	~1.420 - 1.425

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.