Description

4-Fluorobutanol is a valuable fluorinated alcohol building block, offering a unique combination of reactivity and fluorine atom properties for advanced chemical synthesis. Its primary value lies in its role as a versatile intermediate for introducing fluorinated moieties into target molecules, which can significantly alter their physical, chemical, and biological properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors, where it is used to develop novel active ingredients, liquid crystals, and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs) and prodrugs, where fluorine substitution can enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging fluorine's ability to improve lipophilicity and environmental persistence of active compounds.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens in the manufacture of high-performance liquid crystal displays (LCDs) and optical devices.
• Polymer & Material Science: Acts as a monomer or modifier in the synthesis of specialty fluoropolymers and surface-active agents, imparting oil/water repellency and chemical resistance.
• Organic Synthesis Reagent: Utilized in nucleophilic substitution reactions and as a protecting group or linker in complex multi-step synthetic routes.
• Fluorine Chemistry Research: A fundamental reagent in academic and industrial R&D for exploring new fluorination methodologies and creating novel fluorinated compounds.

Basic Information

Product Name	4-Fluorobutanol
CAS No.	61599-24-4
Molecular Formula	C4H9FO
Molecular Weight	92.11 g/mol
Synonyms	4-Fluorobutan-1-ol; 1-Fluoro-4-hydroxybutane; 4-Fluoro-1-butanol; ω-Fluorobutyl alcohol; Butanol, 4-fluoro-; 4-Fluorobutyl alcohol; 61599-24-4; 4-Fluoro-n-butanol
EINECS	Contact for details

Quality Control

Our 4-Fluorobutanol is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay and impurity profiles. We support compliance with global regulatory frameworks, including REACH, and can tailor specifications to meet specific customer or pharmacopeial requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Gravity (20°C)	1.050 - 1.090
Refractive Index (n20D)	1.410 - 1.420

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.